翁建平的個(gè)人首頁

翁建平醫(yī)生簡介

  翁建平 醫(yī)學(xué)博士,教授,主任醫(yī)師,博士生導(dǎo)師,中山大學(xué)附屬第三醫(yī)院副院長。教育部國家重點(diǎn)學(xué)科中山大學(xué)內(nèi)分泌學(xué)科學(xué)術(shù)負(fù)責(zé)人兼首席專家。主要學(xué)術(shù)任職有中華醫(yī)學(xué)會(huì)糖尿病學(xué)分會(huì)副主任委員兼秘書長、中華醫(yī)學(xué)會(huì)內(nèi)分泌學(xué)會(huì)委員、亞洲分子糖尿病學(xué)理事會(huì)理事、廣東省醫(yī)學(xué)會(huì)糖尿病學(xué)會(huì)主任委員、廣東省糖尿病防治研究中心主任;《中華內(nèi)科雜志》,《中華糖尿病雜志》及《中華內(nèi)分泌代謝雜志》編委、《中國實(shí)用內(nèi)科雜志》常務(wù)編委等職。

  教育和工作簡歷:

  1985年獲東南大學(xué)醫(yī)學(xué)院(南京鐵道醫(yī)學(xué)院)醫(yī)學(xué)學(xué)士;

  1991年獲中山大學(xué)(中山醫(yī)科大學(xué))內(nèi)分泌專業(yè)醫(yī)學(xué)碩士;畢業(yè)后留校歷任住院總醫(yī)生、主治醫(yī)生;

  1996年獲中山大學(xué)醫(yī)學(xué)博士,

  1997年破格晉升副教授、副主任醫(yī)師,

  1997.12~2000.3瑞典LUND大學(xué)博士后,從事糖尿病分子遺傳學(xué)研究

  2000年7月任中山大學(xué)附屬第一醫(yī)院內(nèi)分泌科主任

  2001.12破格晉升教授、主任醫(yī)師

  2005年.9月~2007年9月中山大學(xué)附屬第一醫(yī)院內(nèi)分泌科首席專家

  2007.10~中山大學(xué)附屬第三醫(yī)院,任副院長,主管科研及學(xué)科建設(shè)。

  主要研究方向:

  2 型糖尿病早期干預(yù)、特殊類型糖尿病分子遺傳學(xué)研究等方面有很深的造詣。獲 973一級(jí)分題(2型糖尿病營養(yǎng)干預(yù)代謝組學(xué)課題組長)、國家自然科學(xué)基金2項(xiàng)、衛(wèi)生部重點(diǎn)臨床項(xiàng)目、廣東省自然科學(xué)基金重點(diǎn)項(xiàng)目及中山大學(xué)5010計(jì)劃項(xiàng)目等多項(xiàng)課題資助。在包括 Diabetes、Diabetologia、Diabetes Care及JCEM 等國內(nèi)外雜志發(fā)表學(xué)術(shù)論文100 余篇。2006年以“胰島B細(xì)胞功能和2型糖尿病關(guān)系的實(shí)驗(yàn)和臨床研究”獲教育部科技進(jìn)步一等獎(jiǎng);2007年獲中國胰島素分泌年度成就獎(jiǎng)。

  發(fā)表論文:

  在國內(nèi)外核心雜志發(fā)表論文約100余篇,主要英文論文摘錄如下:

  1. Weng J., Marfarlane W. M., Lehto M., Gu F, Hattersley A. T., Groop L. Functional consequence of mutations in MODY4 gene (IPF1) and presentation in families with MODY3 mutatoins. Diabetologia 2001, 44:249-258(IF:5.6)

  2. Weng J, Lehto M, Forsblom C, et al. The hepatocyte nuclear factor –1 (MODY5) gene mutations in Scandinavian families with early-onset diabetes and/or kidney disease. Diabetologia 2000, 43:131-132(IF:5.6)

  3. Weng J., Ekelund M, Lehto M, Li H, Ekberg G, Frid A, Aberg A, Groop L and Berntorp K. Screening for the MODY mutaions, GAD antibodies, and type 1 diabetes-associated HLA genotypes in women with gestational diabetes. Diabetes Care 2002, 25(1):68-71(IF:7.884)

  4. Weng J.(通信作者), Lehto M., Berglund A., Groop L. C. An Automated Fluorescent Single-Strand Conformation Polymorphism Technique for High Throughput Mutational Screening. Chinese Medical Journal 2001,114(11): 1147-1150

  5. WENG J, YAN J, HUANG Z, SUI Y, XIU L. Missense mutation of Pro387Leu in protein tyrosine phosphatase-1B (PTP-1B) is not associated with type 2 diabetes in a Chinese Han population. Diabetes Care. 2003 Oct;26(10):2957(通信作者,IF:7.884)

  6. Yanbing Li MD, Wen Xu MD, Zhihong Liao MD & PhD, Bin Yao MD, Xiahua Chen MD, Zhimin Huang MD, Guoliang Hu MD and Jianping Weng MD & PhD. Induction of Long-term Glycemic Control in Newly Diagnosed Type 2 Diabetic Patients is Associated with Improvement of Beta-cell Function. Diabetes Care 2004, 27(11):2957-2602(通信作者, IF:7.884)

  7. Yan J, Gao Z, Yu G, He Q, Weng J, Ye J. Nuclear Corepressor Is Required for Inhibition of Phosphoenolpyruvate Carboxykinase Expression by Tumor Necrosis Factor-a. Mol. Endocrinol. 2007; 21: 1630 – 1641(翁建平通信作者, IF: 5.84)

  8. Huang X, Vaag A, Weng J, Laurila E, Groop L. Impaired insulin-stimulated expression of the glycogen synthase gene in skeletal muscle of type 2 daibetic patients is acquired rather than inherited. J Clin Endocrinol Metab 2000, 85:1584-1590 (IF:6.02)

  9. Lindgren C. M., Widen E., Li H., Melander O., Almgren P., Lehto M., Weng J. and Groop L. Contribution of known and unknown susceptibility genes to early-onset diabetes in Scandinavia - evidence for heterogeneity. Diabetes 2002 May;51(5):1609-17(IF: 8.028)

  10. Lehto M,. Wipemo C., Ivarsson S-A., Weng J., Groop L.C .. High freguency of mutations in MODY and mitochondrial genes in Scandinavian patients with familial early-onset diabetes. Diabetologia 1999, 42:1131-1137(IF:5.6)

  11. Li H, Groop L, Nilsson A, Weng J, Tuomi T. A combination of human leukocyte antigen DQB1*02 and the tumor necrosis factor alpha promoter G308A polymorphism predisposes to an insulin-deficient phenotype in patients with type 2 diabetes.

  J Clin Endocrinol Metab. 2003 Jun;88(6):2767-74. (IF:6.02)